Replying to @April This is the first and only B supplement that I have noticed such a difference with! It’s completely opened my eyes to why we all feel the way we do and how connected our systems are. Along with the importance of supplements and nutrition! More Info: Folic acid fortification began in 1998, but for those with MTHFR and related gene mutations (MTR, MTRR, COMT, BHMT, CBS, SHMT1), synthetic folic acid can be difficult to process, leading to methylation issues, impaired detoxification, and neurotransmitter imbalances. Proper B vitamins, especially methylated folate (5-MTHF) and B12 (methylcobalamin), are crucial for supporting methylation, hormone regulation, and brain function. This is particularly important for people with PMDD and ADHD, as genes like MTHFR and COMT affect dopamine levels, estrogen metabolism, and mood stability. Ensuring the right forms of B vitamins—rather than synthetic folic acid—can help optimize neurotransmitter function, reduce inflammation, and support hormonal balance in those with these conditions.
#pmdd #premenstrualdysphoricdisorder #pmddsupport #pmddawareness #pmddstruggles #pmddsymptom #adhdinwomen #afabadhd #adhdcheck #neurodivergent #mthfr