I made pot roast four times in the past week for this video because I was trying to perfect the recipe, and here's what I learned. First, season the chuck heavily! It's really all you need to do. I kept making it too salty by over-seasoning the liquid until it passed the "taste test" before braising. But as it cooks, the salt concentrates and can become overpowering. So, my advice: You can always add more salt, but you can't take it out. Season generously, and when it's time to reduce your sauce, adjust the seasonings as you see fit. For me, the way I made it is very close to perfect.
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